Pii: S0167-5699(00)01750-3

نویسندگان

  • P. J. Kraulis
  • E. A. Merritt
  • M. E. P. Murphy
چکیده

with EBV: polyreactive antibodies and CD5 B lymphocytes. Annu. Rev. Immunol. 7, 513–525 52 Kipps, T. and Carson, D.A. (1993) Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases. Blood 81, 2475–2487 53 Diehl, L.F. and Ketchum, L.H. (1998) Autoimmune disease and chronic lymphocytic leukemia: autoimmune hemolytic anemia, pure red cell aplasia, and autoimmune thrombocytopenia. Semin. Oncol. 25, 80–97 54 Fehr, T. et al. (1996) T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal. Cell. Immunol. 168, 184–192

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29 Winter, G. et al. (1994) Making antibodies by phage display technology. Annu. Rev. Immunol. 12, 433–455 30 Jakobovits, A. et al. (1995) Production of antigen-specific human antibodies from mice engineered with human heavy and light chain YACs. Ann. New York Acad. Sci. 764, 525–535 31 Wagner, S.D. et al. (1994) The diversity of antigen-specific monoclonal antibodies from transgenic mice beari...

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has gained widespread acceptance as a tool for quantifying cells that possess observable functional activities. Thoroughly planned titration experiments can produce straightforward and interpretable single-hit kinetics, whereas analyses of unfractionated cell populations over a broader dilution range result in data that deviate from linearity and do not adhere to all-or-none functionality (e.g....

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3 4 2 V o l . 2 1 N o . 7 J U L Y 2 0 0 0 PII: S0167-5699(00)01658-3 18 Lombardi, G. et al. Type-1 interferon maintains the survival of anergic CD41 T cells. J. Immunol. (in press) 19 Gombert, W. et al. (1996) Fibroblasts prevent apoptosis of IL-2deprived T cells without inducing proliferation: a selective effect on Bcl-x(L) expression. Immunology 89, 397–404 20 Lenardo, M.J. (1997) The molecul...

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sponses are characteristic of autoimmune and infectious diseases. In recent years, substantial progress has been made in understanding the immunological basis of organ-specific autoimmune responses, whereby cell destruction by self-reactive immune effector cells leads to specific tissue pathology and disease1–3. More recently, significant advances have been made in understanding how some viruse...

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11 Murali-Krishna, K., Altman, J.D., Suresh, M. et al. (1998) Immunity 8, 177Ð187 12 Gallimore, A., Glithero, A., Godkin, A. et al. (1998) J. Exp. Med. 187, 1383Ð1393 13 Dunbar, P.R., Ogg, G.S., Chen, J., Rust, N., van der Bruggen, P. and Cerundolo, V. (1998) Curr. Biol. 8, 413Ð416 14 Callan, M.F.C., Tan, L., Annels, N. et al. (1998) J. Exp. Med. 187, 1395Ð1402 15 Borthwick, N.J., Bofill, M., G...

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تاریخ انتشار 2000